Where Is the Drug? Quantitative 3D Distribution Analyses of Confined Drug-Loaded Polymer Matrices

Comparison of the Anti-Fungal Effect of Electro-Spinning Drug-Loaded Nano-Fibers and Pad Dry Drug-Loaded Fabrics

Evaluation by quantitative image analysis of anticancer drug activity on multicellular spheroids grown in 3D matrices

Pharmacological evaluation of anticancer drugs using 3D in vitro models provides invaluable information for predicting in vivo activity. Artificial matrices are currently available that scale up and increase the power of such 3D models. The aim of the present study was to propose an efficient and robust imaging and analysis pipeline to assess with quantitative parameters the efficacy of a parti...

Where is the Future of Drug Discovery for Cancer?

With both small molecules and biologics succeeding in trials and in the clinic, the scope of drug discovery in cancer is changing. We asked a group of researchers to share their visions for how to identify new targets and how to approach taming them.

Transferosome: the Drug Loaded Ultradeformable Vesicles for Transdermal Drug Delivery

Now a days, The novel drug delivery system is creating a new interest in development of drug deliveries. Vesicular drug delivery system in also a part of this novel drug delivery system which is designed according to the recent demands of treatment like sustain release of drug in systemic circulation, definite dosing interval. Transferosomes are part of this vesicular drug delivery system which...

Synthesis of magnetically active interpenetrating polymer network for drug release

Interpenetrating polymer networks (IPN) were formed involving hydrophobic polybutyl acrylate (PBA) and hydrophilic poly hydroxyethyl acrylate (PHEA). PBA prepolymer was first formed in presence of ferric oxide nanoparticles (